The seismic risk assessment and resiliency of the urban city requires the robust procedure by reflecting multidisciplinary research aspects into the loss modeling. However, the risk study in the United Arab Emirates (UAE) is limited because the reginal data and hazard models are limited. Moreover, the platform is required that combines these regional models into the loss estimations. Since large uncertainties exist in the hazard models for multiple aspects such as ground motion attenuations, site amplification, regional structural fragility, and the loss modeling related to the regional network, it is important to understand the impact of uncertainties on loss estimation to effectively conduct the future researches. This study presents a seismic loss estimation by the scenario earthquakes occurred in Iran, which is approximately 100-km offshore in UAE.